Apollone premio alessandro via san donato 115

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"Energy metabolism in tumor cells".
Almost all ions and molecules require special membrane transporters to enter or exit the matrix.
19 The first high-resolution electron micrographs appeared in 1952, replacing the Janus Green stains as the preferred way of visualising the mitochondria.Warburg and Heinrich Otto Wieland, who had also postulated a similar particle mechanism, disagreed on the chemical nature of the respiration.A b c d Decuypere JP, Monaco G, Bultynck G, Missiaen L, De Smedt H, Parys JB (May 2011).Cell Death and Differentiation.In humans, 615 distinct types of protein have been identified from cardiac mitochondria, 16 whereas in rats, 940 proteins have been reported.23 In 1967, it was discovered that mitochondria contained ribosomes.

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Mitochondrial matrix calcium levels can reach the tens of micromolar levels, which is necessary for the activation of isocitrate dehydrogenase, one of the key regulatory enzymes of the Krebs cycle.